Capretta Group


Last 5 years

Year Title Journal Volume Pages Authors
2015 A Fluorous Analogue of Chloramine-T: Preparation, X-Ray Structure Determination and Use as an Oxidant for Radioiodination and s-Tetrazine Synthesis J. Org. Chem. Dzandzi, James P. K.; Beckford Vera, Denis R.; Genady, Afaf R.; Albu, Silvia A.; Eltringham-Smith, Louise J.; Capretta, A.; Sheffield, William Peter; Valliant, John F View
2014 Carbon monoxide-releasing molecule 3 inhibits myeloperoxidase (MPO) and protects against MPO-induced vascular endothelial cell activation/dysfunction Free Radical Biology and Medicine 70 167-173 Patterson, Eric K.; Fraser, Douglas D.; Capretta, Alfredo; Potter, Richard F.; Cepinskas, Gediminas View
2013 Structure-Guided Optimization of Protein Kinase Inhibitors Reverses Aminoglycoside Antibiotic Resistance. Biochem 454 191-200 Stogios, Peter J.; Spanogiannopoulos, Peter; Evdokimova, Elena; Egorova, Olga; Shakya, Tushar; Todorovic, Nick; Capretta, Alfredo; Wright, Gerard D.; Savchenko, Alexei. View
2013 A Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Method for Direct Screening of Small Molecule Mixtures Against an Aminoglycoside Kinase. Anal. Chim Acta 786 103-110 Smith, Anne Marie E.; Awuah, Emelia; Capretta, Alfredo; Brennan, John D. View
2013 Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA Med Chem Lett 23 2426-2431 Barker, Courtney; Allison, Sarah; Zlitni, Soumaya; Nguyen, Nick Duc; Das, Rahul; Melacini, Giuseppe; Capretta, Alfredo; Brown, Eric D View
2013 HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy Molecular Therapy 21 887-894 Bridle, Byram W.; Chem, Lan; Lemay, Chantal G.; Diallo, Jean –Simon; Pol, Jonathon; Nguyen, Andrew; Capretta, Alfredo; He, Rongqiao; Bramson, Jonathan L.; Bell, John C.; Lichty, Brian D.; Wan, Yonghong View
2012 The Chemical Perturbation of Secondary Metabolism Demonstrates Important Links to Primary Metabolism Chemistry & Biology 19 1020-1027 Craney, A.; Ozimok, C.; Capretta, A.; Nodwell, J. R. View
2012 Transition State Analysis of Enolpyruvylshikimate 3-Phosphate Synthase (AroA)-Catalyzed EPSP Hydrolysis. Chem. Soc 134 12958-12969 Lou, M.; Burger, S. K.; Gilpin, M. E.; Gawuga, V.; Capretta, A.; Berti, P. J. View
2012 Transition State Analysis of Acid-Catalyzed Hydrolysis of an Enol Ether, Enolpyruvylshikimate 3-Phosphate (EPSP) Chem. Soc 134 12947-12957 Lou, M.; Gilpin, M. E.; Burger, S. K.; Malik, A. M.; Gawuga, V.; Popovic, V.; Capretta, A.; Berti, P. J. View
2011 Synthesis of Substituted Isoquinolines via Pd-Catalyzed Cross Coupling Approaches. Org. Lett 13 6180-6183 Todorovic, N.; Awuah, E.; Albu, S.; Ozimok, C.; Capretta. A View
2011 Microwave-assisted Synthesis of N1- and C3-substituted Pyrazolo[3,4-d]pyrimidine Libraries. Tetrahedron Lett 52 5761 – 5763 Todorovic, N.; Awuah, E.; Shakya, T.; Wright, G.D.; Capretta. A. View
2011 Development of Methods for the Synthesis of Libraries of Substituted Maleimides and alpha, beta-Unsaturated-gamma-Butyrolactams J. Org. Chem. 76 3122–3130 Awuah, E.; Capretta, A. View
2011 Polymethylene-Interrupted Fatty Acids: Biomarkers for Native and Exotic Mussels in the Laurentian Great Lakes Journal of Great Lakes Research 37 289 -297 Mezek, T.; Sverko, E.; Rudy, M.D.; Zaruk, D.; Capretta, A.; Hebert, C.E.; Fisk, A.T.; McGoldrick, D.J.; Newton, T.J.; Sutton, T.S.; Koops, M.A.; Muir, A.M.; Johnson, T.B.; Ebener, M.P.; Arts, M.T. View
2011 Synthesis of Deuterated 5(Z),11(Z)-Eicosadienoic Acid as a Biomarker for Trophic Transfer. Tetrahedron Letters 52 787-788 Albu, S.; Sverko, E.; Arts, M. T.; Capretta, A. View

Older than 5 years

Year Title Journal Volume Pages Authors
2010 Microwave-assisted Synthesis of 3-Aryl-Pyrimido[5,4e][1,2,4]triazine-5,7(1H,6H)-dione Libraries: Derivatives of Toxoflavin. Tetrahedron Letters 51 6037 – 6040 Todorovic, N.; Giacomelli, A.; Hassell, J.A.; Frampton, C.S.; Capretta, A. View
2010 Carbon monoxide-releasing molecule CORM-3 suppresses vascular endothelial cell SOD-1/SOD-2 activity while up-regulating the cell surface levels of SOD-3 in a heparin-dependent manner. Free Radical Biology and Medicine 49 1534-1541 Mizuguchi, S.; Capretta, A.; Suehiro, S.; Nishiyama, N.; Luke, P.; Potter, R.F.; Fraser, D.D.; Cepinskas, G. View
2010 Strategies and Synthetic Methods Directed Towards the Preparation of Libraries of Substituted Isoquinolines. J. Org. Chem. 75 5627–5634 Awuah, E.; Capretta, A View
2010 Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells. Am J Physiol Endocrinol Metab 298 E499-511 Sage, A. T.; Walter, L. A.; Shi, Y.; Khan, M. I.; Kaneto, H.; Capretta, A.; Werstuck, G. H. View
2009 CO-releasing molecule (CORM-3)-derived CO modulates neutrophil (PMN) migration across vascular endothelium by reducing the levels of cell surface-bound elastase. Am J Physiol Heart Circ Physiol 297 H920-929 Mizuguchi, S.; Stephen, J.; Dencev-Bihari, R.; Markovic, N.; Suehiro, S.; Capretta, A.; Potter, R. F.; Cepinskas, G. View
2009 Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting. Nat Chem Biol 5 849-856 Pathania, R.; Zlitni, S.; Barker, C.A.; Das, R.; Awuah, E.; Lebert, J.; Melacini, G.; Capretta, A.; Brown, E.D. View
2009 Access to Flavones via a Microwave-assisted, One Pot Sonogashira-Carbonylation-Annulation Reaction Org. Lett 11 3210-3213 Awuah, E.; Capretta, A. View
2009 A synthesis of sulfonamide analogs of platensimycin employing a palladium-mediated carbonylation strategy Tetrahedron Letters 50 4087-4091 McNulty, J.; Nair, J. J.; Capretta, A. View
2008 An ESI-MS/MS Method for Screening of Small-Molecule Mixtures against Glycogen Synthase Kinase-3beta (GSK-3beta) ChemBioChem 9 1065-1073 Partserniak, I.; Werstuck, G.; Capretta, A.; Brennan, J. D. View
2008 A Convenient Method for the Preparation of Fluorous Tin Derivatives for the Fluorous Labeling Strategy. J. Org. Chem. 73 8236-8243 McIntee , J. W.; Sundararajan, C.; Donovan, A. C.; Kovacs, M. S.; Capretta, A.; Valliant, J. F. View
2008 A robust strategy for the preparation of libraries of metallopeptides. A new paradigm for the discovery of targeted molecular imaging and therapy agents. Chemical Communications 43 5532-5534 Armstrong, A. F.; Oakley, N.; Parker, S.; Causey, P. W.; Lemon, J.; Capretta, A.; Zimmerman, C.; Joyal, J.; Appoh, F.; Zubieta, J.; Babich, J. W.; Singh, G.; Valliant, J. F. View
2007 Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition. Bioorg Med Chem Lett 17 4491-4494 Shi, Y.; Gerritsma, D.; Bowes, A. J.; Capretta, A.; Werstuck, G. H., View
2006 Scope and Mechanistic Insights into the Use of Tetradecyl(trihexyl)phosphonium Bistriflimide: A Remarkably Selective Ionic Liquid Solvent for Substitution Reactions Chemistry - A European Journal 12 9314-9322 McNulty, J.; Nair, J. J.; Cheekoori, S.; Larichev, V.; Capretta, A.; Robertson, A. J. View
2006 Phosphorinanes as Ligands for Palladium-Catalyzed Cross-Coupling Chemistry. Org. Lett 8 103-105 Brenstrum, T.; Clattenburg, J.; Britten, J.; Zavorine, S.; Dyck, J.; Robertson, A. J.; McNulty, J.; Capretta, A View
2006 Rhodium Phosphinates as Catalysts for Metal-Stabilized Carbene Chemistry: Synthesis, Characterization, and Application of Rh2(O2PMe2)4. Organometallics 25 32-34 Adjabeng, G. M.; Gerritsma, D. A.; Bhanabhai, H.; Frampton, C. S.; Capretta, A. View
2005 A mild esterification process in phosphonium salt ionic liquid. Tetrahedron Letters 46 3641-3644 McNulty, J.; Cheekoori, S.; Nair, J. J.; Larichev, V.; Capretta, A.; Robertson, A. J View
2005 imethylmalonyltrialkylphosphoranes: probing the steric effect on phosphorus and its stereochemical consequence in esterification reactions of chiral secondary alcohols. Journal of Organometallic Chemistry 690 2548-2552 Dyck, J.; Zavorine, S.; Robertson, A. J.; Capretta, A.; Larichev, V.; Britten, J.; McNulty, J View
2004 Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds Bioorganic & Medicinal Chemistry Letters 14 5465-5467 Werstuck, G. H.; Kim, A. J.; Brenstrum, T.; Ohnmacht, S. A.; Panna, E.; Capretta, A. View
2004 Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework. Tetrahedron Letters 45 5661-5663 Ohnmacht, S. A.; Brenstrum, T.; Bleicher, K. H.; McNulty, J.; Capretta, A. View
2004 Phosphonium Salt Catalyzed Nitroaldol Reactions. Letters in Organic Chemistry 1 137-139 McNulty, J.; Dyck, J.; Laritchev, V.; Capretta, A.; Robertson, A. J. View
2004 Phosphonium Salts as Room-Temperature Ionic Liquids in Organic Synthesis Chimica Oggi 22 13-16 McNulty, J.; Capretta, A.; Cheekoori, S.; Clyburne, J. A. C.; A.J., R.
2004 Heck reactions of aryl halides in phosphonium salt ionic liquids: library screening and applications Tetrahedron Letters 45 7629-7631 Gerritsma, D. A.; Robertson, A.; McNulty, J.; Capretta, A. View
2004 Phospha-adamantanes as ligands for organopalladium chemistry: aminations of aryl halides Tetrahedron Letters 45 8319-8321 Gerristma, D.; Brenstrum, T.; McNulty, J.; Capretta, A. View
2004 Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry: Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing beta-Hydrogens with Boronic Acids and Alkylboranes. Org. Chem. 69 7635-7639 Brenstrum, T.; Gerristma, D. A.; Adjabeng, G. M.; Frampton, C. S.; Britten, J.; Robertson, A. J.; McNulty, J.; Capretta, A. View
2004 Palladium Complexes of 1,3,5,7-Tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane: Synthesis, Crystal Structure and Use in the Suzuki and Sonogashira Reactions and the alpha-Arylation of Ketones. J. Org. Chem 69 5082-5086 Adjabeng, G.; Brenstrum, T.; Frampton, C. S.; Robertson, A. J.; Hillhouse, J.; McNulty, J.; Capretta, A. View
2003 On the Role of Acyloxyphosphonium Ions and Stereochemical Influence of Base in Phosphorane Mediated Esterification Reactions Angew. Chem. Int. Ed. Engl 42 4051-4054 J. McNulty, A. Capretta, A. Robertson, A.J. Larichev, J. Dyck View
2003 Novel Class of Tertiary Phosphine Ligands Based on a Phosphaadamantane Framework and Use in Suzuki Cross-Coupling Reactions of Aryl Halides Under Mild Conditions. Org. Lett 5 953 Adjabeng, T. Brenstrum, J.Wilson, C. Frampton, A. Robertson, J. Hillhouse, J. McNulty, and A. Capretta View
2003 Lipase-Catalyzed Stereoselective Resolution and Desymmetrization Binaphthols. Tetrahedron: Asymmetry 14 289-291 M. Juarez-Hernandez, D. V. Johnson, H. H. Holland, J. McNulty and A. Capretta View
2003 Dimethylmalonyltrialkylphosphoranes: New General Reagents for Esterification Reactions Involving Controlled Inversion or Retention of Configuration on Chiral Alcohols. Journal of Organic Chemistry 68 1597-1600 J. McNulty, A. Capretta, V. Laritchev, J. Dyck and A.J. Robertson. View
2003 Preparation of Labelled 2-Methoxy-3-Alkylpyrazines: Synthesis and Characterization of Deuterated 2-Methoxy-3-Isopropylpyrazine and 2-Methoxy-3-Isobutylpyrazine. Journal of Labelled Compounds and Radiopharmaceuticals. 46 243 D. A. Gerritsma, I. D. Brindle, T.R.B. Jones, and A. Capretta. View
2002 Synthesis of substituted imidazoles from 1,2-aminoalcohols. Tetrahedron Letters 43 7687-7690 K. Bleicher, F. Gerber, Y. Wüthrich, A. Alanine and A. Capretta View
2002 Suzuki Cross-Coupling Reactions of Aryl Halides in Phosphonium Salt Ionic Liquids Under Mild Conditions. Journal of the Chemical Society, Chemical Communications - 1986-1987 J. McNulty, A. Capretta, J. Wilson, J. Dyck, G. Adjabeng and A. Robertson, View
2002 Sensitization of Lanthanides by Nonnatural Amino Acids Photochemistry and Photobiology 75 117-121 J. D. Brennan, A. Capretta, K. Yong, D. Gerritsma, K.K. Flora, and A. Jones. View
2001 Chiral Phosphine Ligands Derived From Terpenes: The Synthesis and Structure of 4,8-Dimethyl-2-Phosphabicyclo[3.3.1]nonane. Tetrahedron Letters 42 2609-2612 A. Roberston, C. Bradaric, C. S. Frampton, J. McNulty, and A. Capretta View
2001 A New Structural Motif For Rigid C2-Symmetrical Propeller-Shaped 1,2-Diamines Employing Double Aromatic pi-Stacking Journal of the Chemical Society, Chemical Communications - 2384-2385 J. McNulty, R. Mo, A. Capretta and C. S. Frampton View
2000 Intramolecular Carbenoid Insertions: The Reactions of alpha-Diazoketones Derived From Pyrrolyl and Indolyl Carboxylic Acids with Rhodium (II) Acetate. Tetrahedron 56 8063-8069 Mohamed Salim and Alfredo Capretta. View
1998 Intermolecular Carbenoid Insertions: Reactions of 2-Substituted Thiophenes with Ethyl Diazoacetate in the Presence of Rhodium (II) Acetate Tetrahedron 54 15499-15509 Geoffrey K. Tranmer and Alfredo Capretta. View
1998 Intramolecular Carbenoid Insertions: The Reactions of alpha-Diazoketones Derived From Furanyl, Thienyl, Benzofuranyl and Benzothienyl Acetic Acids with Rhodium (II) Acetate Journal of Organic Chemistry 63 9828-9833 Kelvin Yong, Mohamed Salim and Alfredo Capretta. Intramolecular View
1997 Intramolecular Carbenoid Insertions Into Thiophene: Reactions of 1-Diazo-3-(2-Thienyl)-2-Propanone and 1-Diazo-3-(3-Thienyl)-2-Propanone. Tetrahedron Letters 38 5081 Christopher S. Frampton, David L. Pole, Kelvin Yong and Alfredo Capretta. View
1996 Biosynthesis of Porphyrins and Related Macrocycles. Part 45. Determination by a Novel X-Ray Method of the Absolute Configuration of the Spirolactam which Inhibits Uroporphyrinogen III Synthase (Cosynthetase). Journal of the Chemical Society, Perkin Transactions 1 - 2079-2090 A.C. Spivey, A. Capretta, C. S. Frampton, F. J. Leeper and A. R. Battersby View
1995 Expression, Purification and Characterisation of the Product from the Bacillus subtilis hemD Gene, Uroporphyrinogen III Synthase. European Journal of Biochemistry 231 236-241 N. Patrick J. Stamford, Alfredo Capretta, and Alan R. Battersby. View
1995 Synthesis and Characterization of Cyclomaltoheptaose-based Metal Chelants as Probes for Intestinal Permeability. Carbohydrate Research 267 49-63 Alfredo Capretta, Rabindranath B. Maharajh and Russell A. Bell. View
1995 Stereochemical Studies on the Proposed Spiro Intermediate for the Biosynthesis of Natural Porphyrins: Determination by a Novel X-Ray Method of the Absolute Configuration of the Spirolactam which Inhibits Cosynthetase. Journal of the Chemical Society, Chemical Communications. - 1789-1790 Alan C. Spivey, Alfredo Capretta, Christopher S. Frampton, Finian J. Leeper and Alan R. Battersby. View
1995 Synthesis, NMR and Ultraviolet Spectroscopy of [10](N6,9)-6-Aminopurinophane; Calculation of the Chemical Shifts in the [n](N6,9)-6-Aminopurinophane Series. Canadian Journal of Chemistry. 73 2224-2232 Alfredo Capretta and Russell A. Bell. View